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CPS Instruments - Worlds leading Disc Centrifuge Manufacturer

News Overview


  • European Introduction of the NEW CPS DC24000 UHR
  • Intertek MSG Choose CPS Disc Centrifuge for Nano-Particle Characterisation
  • CPS User Seminar
  • BegbrokeNano Uses CPS Disc Centrifuge for Nanoparticle Characterisation
  • Analytical Ultracentrifugation: Techniques and Methods
  • CPS Disc Centrifuge at Janssen Pharmaceutica
  • BePCIS


    News



    European Introduction of the NEW CPS DC24000 UHR

    CPS Instruments proudly announced the European Introduction of the NEW CPS DC24000 UHR.

    The CPS DC24000 UHR sets a new standard in High Resolution particle size measurements. The key features of this instrument compared to the older CPS Disc Centrifuges are:

  • Higher Resolution
  • Quiet Operation
  • Improved Solvent Resistant Disc
  • Added Operating Flexibility

    The NEW DC24000 UHR

    You can download here the leaflet of the CPS DC24000 UHR.


    Intertek MSG Choose CPS Disc Centrifuge for Nano-Particle Characterisation

    Intertek MSG has recently conducted a wide-ranging evaluation of commercially available instrumentation for analysing particle size distributions in nano-particle dispersions. Following this extensive review Intertek MSG chose to purchase the CPS DC24000 Disc Centrifuge instrument to complement their already impressive range of equipment for materials characterisation.

    Example of Resolution possible down to 15 nm using a mixture of Gold Particles This model of CPS Disc Centrifuge has the capability to resolve multi-modal particle distributions as is shown in the figure below. Here, a number of separate populations of gold particles with diameters down to around 15 nm are being analysed. Depending on particle density, the CPS Disc Centrifuge can be configured (using a variety of run conditions) to accurately measure particle diameters between 3 nm and 75 microns.

    Dr. Bill Meredith making a sample injection on Intertek MSG's new CPS Disc Centrifuge. An autosampler was also purchased to enable fully unattended automatic injection of multiple samples and standards. Intertek MSG has been providing measurement science services to a range industries including the ICI Group (of which it used to be a part) for the last 30 years. Intertek MSG is one of the core providers for the NanoCentral project, a DTI-funded initiative that aims to facilitate nanomaterial commercialisation, and has made specific instrument purchases to widen the range of services that it offers.

    Dr. Bill Meredith, Team Leader of the Particle Sizing section at Intertek MSG, said ; "Accurate, consistent, but also high resolution analysis of nano-particle distributions in aqueous and non-aqueous liquids is very important in the highly varied work we do for our customers. Our existing instruments such as PCCS and laser diffraction are very useful, but in some cases they either do not tell the whole story or cannot analyse the very small, eg. sub-50 nm, particles, to the required resolution. The CPS Disc Centrifuge therefore complements our current particle sizing equipment extremely well."

    For more information on Intertek MSG facilities please visit www.measurementscience.co.uk.


    CPS User Seminar

    CPS Instruments Europe and L.O.T-Oriel organised 2 CPS Disc Centrifuge Users Seminars in Germany. With over 50 users attending it was a very successful event. We would like to thank all users for their participation.









    BegbrokeNano Uses CPS Disc Centrifuge for Nanoparticle Characterisation

    BegbrokeNano recently conducted an extensive evaluation of commercially available sub-micron particle size analysers in conjunction with Oxonica. Following this the decision was made to expand its already impressive range of particle and material characterisation instrumentation with the CPS DC24000 High Speed Disc Centrifuge.

    Resolution of 9 Mixed Calibration Standards Measured on the CPS Disc Centrifuge The CPS Disc Centrifuge has capability to resolve multi-modal particle distributions as close as within 2%. This ultra high resolution performance is completely unique and offers the possibility to detect and measure extremely small changes and differences in particle size, especially in the sub-micron particle size range. Depending on density the CPS Disc Centrifuge can accurately and reproducibly measure particles between 3nm and around 75 micron.

    Dr. Monica Ratoi of BegbrokeNano using the new CPS Disc Centrifuge BegbrokeNano (Oxford Materials Characterisation Service) was established in October 2002 as a point of contact for those wishing to access facilities and expertise within the University of Oxford, Department of Materials. BegbrokeNano is one of the DTI funded UK Micro Nano Technology (MNT) Centres of Excellence and aims to provide companies involved in MNT with unrivalled facilities for materials characterisation. BegbrokeNano in partnership with leading analytical equipment manufacturers provide a dedicated suite for the analysis of micro and nanoscaled structures.

    Dr. Alison Crossley, Manager of the BegbrokeNano facility said: "High resolution sub-micron particle sizing is one of our priorities. Traditional techniques such as DLS (dynamic light scattering) are extremely useful tools but do not always tell the whole story. The ability of the CPS Disc Centrifuge to detect and measure small differences and changes in particle size distribution enables us to look at, for example, coating thickness on core and shell nanoparticle structures."

    For more information on BegbrokeNano (Oxford Materials Characterisation Service) facilities please visit www.begbrokenano.com.


    Analytical Ultracentrifugation: Techniques and Methods

    Analytical Ultracentrifugation has become an increasingly important technique for monitoring the size and shape of biological macromolecules.

    Analytical Ultracentrifugation: Techniques and Methods contains contributions from experts in the field, bringing together the multitude of developments that have taken place in instrumentation and analysis over the past decade into a single volume.

    The book covers the latest methods in analysis along with an extensive introduction for the novice user. Analysis methods in both sedimentation velocity and sedimentation equilibrium are discussed at length. Protein, Protein/DNA, membrane proteins and polymer systems are also explored, along with software developments and non-ideality.

    Chapter 14 is an Introduction to Differential Sedimentation and is based on the CPS Disc Centrifuge DC24000.

    The book is ideal for biochemists, biophysicists and polymer chemists with an interest in analytical ultracentrifugation. The ISBN number is 0-85404-547-3.

    You can order the book either from CPS Instruments Europe or the Royal Society of Chemistry in the UK.


    CPS Disc Centrifuge at Janssen Pharmaceutica

    After an extensive evaluation of commercially available sub-micron particle size analyzers, Janssen Pharmaceutica's (part of Johnson & Johnson) particle characterization department in Beerse - Belgium, has decided to expand its already impressive range of particle sizing analyzers with the CPS DC24000 (High Speed) Disc Centrifuge.

    Arjen Tinke (R) and CPS European Sales Manager Marc Steinmetz (L) during the last stages of the instrument qualification procedure Arjen Tinke, head of the particle sizing lab: "High resolution sub-micron particle sizing has been one of our top priorities for some time. Traditional techniques such as DLS (dynamic light scattering) do not have the resolution we need for our applications. A typical example is looking for traces of very small particles in what appear to be mono-disperse submicron samples. Such small fractions still contain enormous numbers of particles. The consequence is a high surface area which can be directly related to the speed of drug delivery. Measuring these fractions allows us a much better control of the drug delivery properties."

    As a part of the agreement Janssen Pharmaceutica, CPS Instruments Europe and Benelux Scientific agreed on the challenge to make this one the fastest implementations of a new analysis technique at Janssen Pharmaceutica.

    The CPS DC24000 at Janssen Pharmaceutica Jan De Munck, Sales Manager at Benelux Scientific comments: "Traditionally the implementation of a new measurement technique in a pharmaceutical environment is a long and complex process involving FDA regulations and qualification procedures. This process normally starts once the system has been installed and typically takes one year. In this case, we decided to start writing the standard operating procedures before delivery. At the installation, most SOP's were already available allowing Arjen and his team to immediately start with the final testing and qualification. It's great to see all three parties involved working so closely together towards a common goal which had seemed to be unachievable: a successful implementation of a complete instrument qualification process in well under 4 months after delivery!"


    BePCIS

    CPS Instruments Europe is a member of BePCIS: Belgian Particle, Colloid & Interface Society.